The Mouse anti CytokeRatin 8 / KeRatin K8 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CK8, Cytokeratin 8, K2C8, Keratin 8, KO, and KRT8. This antibody recognizes Human, Rat, and Rabbit antigen. The Mouse anti CytokeRatin 8 / KeRatin K8 Antibody has been validated for the following applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot.
Description
CytokeRatins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual cytokeRatin polypeptides are numbered 1 to 20. The various epithelia in the Human body usually express cytokeRatins which are not only characteristic of the type of epithelium, but also related to the degree of matuRation or differentiation within an epithelium. CytokeRatin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeRatin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays